What condition is characterized by pain worsened by activity and relieved with rest?

The condition characterized by pain that worsens with activity and is relieved with rest is degenerative disc disease. This condition occurs due to the deterioration of the intervertebral discs in the spine, leading to decreased disc height and loss of hydration. As a result, movements, especially those that require spinal loading or excessive bending, can exacerbate pain due to increased pressure on the affected discs and surrounding structures. When at rest, the spine is not under load, which allows for a reduction in pain.

Degenerative disc disease typically presents with specific patterns of pain, often limiting activities such as lifting and prolonged sitting or standing. This cycle of pain with activity and relief upon resting is a hallmark feature that differentiates it from other conditions.

Other conditions listed may present with pain, but their patterns do not typically adhere to the same cycle of worsening with activity and relief with rest. For instance, rheumatoid arthritis often involves systemic symptoms, including morning stiffness that improves with movement, while osteoarthritis may worsen with activity but presents with an overall pattern more closely tied to specific joint use rather than rest. Fibromyalgia is characterized by widespread pain and is not confined to patterns associated with discrete movements or rest. The specific nature of the pain associated with degenerative disc disease makes it