What symptom is commonly associated with excessive doses of corticosteroids?

Excessive doses of corticosteroids are commonly associated with fluid retention. Corticosteroids, such as prednisone, can cause the body to retain sodium and water, leading to an increase in extracellular fluid volume. This retention contributes to symptoms such as edema (swelling due to fluid accumulation) and hypertension (high blood pressure) in some patients.

Moreover, corticosteroids can impact the balance of electrolytes, influencing fluid dynamics within the body. This mechanism is particularly evident in conditions where corticosteroids are administered over long periods or at high doses, which can result in noticeable weight gain due to increased fluid retention. Understanding this relationship is crucial for monitoring and managing patients on corticosteroid therapy, as it highlights the need for careful oversight of fluid and electrolyte balance.